Short description:
The project is focused on new models to study the structure, physiology and health of aquatic vertebrates. Special attention will be dedicated to the mechanisms of resistance to hypoxia, oxygenation of key organs under dicing stress, study of the specific microbioma, and relationship between pathogens and host. Techniques will include tissue culture, image analyses, microbioma analyses, immunohistochemistry, Real-Time PCR, CRISPR.
Five publications related to the Research Topic for the interview:
- de Quirós YB, González-Diaz O, Arbelo M, Sierra E, Sacchini S, Fernández A. (2012) Decompression vs. decomposition: distribution, amount, and gas composition of bubbles in stranded marine mammals. Front Physiol. 3:177.
- Griffeth RJ, García-Párraga D, Mellado-López M, Crespo-Picazo JL, Soriano-Navarro M, Martinez-Romero A, Moreno-Manzano V. (2014) Platelet-rich plasma and adipose-derived mesenchymal stem cells for regenerative medicine-associated treatments in bottlenose dolphins (Tursiops truncatus). PLoS One. 9:e108439. doi: 10.1371/journal.pone.0108439
- Yu J, Kindy MS, Ellis BC, Baatz JE, Peden-Adams M, Ellingham TJ, Wolff DJ, Fair PA, Gattoni-Celli S. (2005) Establishment of epidermal cell lines derived from the skin of the Atlantic bottlenose dolphin (Tursiops truncatus). Anat Rec A Discov Mol Cell Evol Biol. 287:1246-55.
- Cui Y, Xu J, Cheng M, Liao X, Peng S. (2018) Review of CRISPR/Cas9 sgRNA Design Tools. Interdiscip Sci. doi: 10.1007/s12539-018-0298-z.
- Place TL, Domann FE, Case AJ. (2017) Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research. Free Radic Biol Med. 113:311-322. doi: 10.1016/j.freeradbiomed.2017.10.003.
